Since 2008 we could complete more than 1200 projects successfully. Following you will find the subjects of the performed studies

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Cardiology

Myocardial Diseases

Cardiology Clinical Research Organization
  • Clinical course of echocardiographic and cardiopulmonary parameters in patients suffering from myocarditis
  • Gender-dependent influences on hypertrophic obstructive cardiomyopathy vs. hypertrophic non-obstructive cardiomyopathy – a multicentre study
  • Determinants of survival after percutaneous transluminal septal myocardial ablation (PTSMA) in patients with HOCM – a long-term follow-up study
  • Incidence of takotsubo syndrome in patients with instable angina pectoris and normal coronary status – consecutive data collection over a period of 5 years
  • Follow-up study of patients with severely reduced left ventricular function suffering from myocarditis – randomized comparison of treatment with interferon vs. conventional medication
  • Prognostic impact of new biomarkers (GDF-15, ST2, hsTNT, sFLT1, PLGF, P1NP, PAPP-A, Endostatin, sFRP3, IGFBP-7, Mimecan, Biglycan, IGF-1, Leptin, Adiponectin, Osteopontin, Galectin-2) in diastolic heart failure 
  • Implementation of guide lines in medical treatment of patients with chronic heart failure
  • Significance of electric muscle stimulation in treatment of chronic cardiac insufficiency
  • Prognostic impact of neurohumoral parameters in patients with cardiac insufficiency
  • Sensitivity and specificity of CTproAVP and NTproBNP in patients with left ventricular dysfunction
  • Prognostic value of lactate and lactate clearance in cardiogenic shock
  • NTproBNP in patients with end stage coronary herat disease and manifest heart failure – comparison of outcome in conventional therapy vs. CABG

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Cardiac valve diseases / Pericardial Diseases / Heart Tumors / Congenital Heart Defects

Valve Diseaes Clinical Research Organization
  • Modification of the Wilkins score to optimize results after percutaneous mitral valve repair – analysis including 300 patients
  • Long-term results after percutaneous mitral valve repair
  • Performance after percutaneous mitral valve repair – a meta analysis 
  • Percutaneous mitral valve repair by clips – comparison of two Systems
  • Clinical course after mitral valve reconstruction with mitral clip technique – a follow-up study
  • Prognosis of patients suffering from high-grade valvular aortic stenosis after TAVI (Transcatheter-aortic valve - implantation)
  • Echocardiographic parameters before and after TAVI (Transcatheter-aortic valve - implantation)
  • Impact of TAVI (Transcatheter-aortic valve - implantation) on atrio-ventricular nervous conduction
  • Outcome after 6 months and hemodynamic parameters before and after TAVI (Transcatheter-aortic valve - implantation)
  • First in men application of TAVI (Transcatheter-aortic valve - implantation)
  • Prognosis and quality of life after TAVI (Transcatheter-aortic valve - Implantation)
  • Description of results after the first TAVI interventions in a university heart centre
  • Outcome and complications after transapical TAVI – comparison of periods 2009 – 2013 vs. 2014 – 2017
  • Speckle tracking analysis of the left ventricular function before and after TAVI (Transcatheter-aortic valve - implantation)
  • Anticoagulation after prosthetic or biological cardiac valve replacement – risk factors for haemorrhages and heart valve thromboses
  • Intrahospital mortality in patients after mechanic tricuspidal valve placement
  • Comparison of tricuspid valve replacement vs. tricuspid valve reconstruction – indication and long-term follow-up
  • Etiology and different treatment of tricuspid valve insufficiency
  • Anticoagulation in patients with complex congentital heart defects
  • Effectivity and haemorrhagic risk of new oral anticoagulants (NOAC) in patients with congenital heart defects
  • Long term follow-up in congenital heart defects – a multicenter study
  • Comparison of long-term follow-up after ASD closure with different devices

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Coronarangiography and Interventional Cardiology

Clinical Research Organization Coronary artery disease
  • Renal parameters before and after coronary angiography in patients with chronic renal insufficiency with vs. without ACC pre-treatment
  • Comparison of the effectiveness of several treatment strategies to avoid contrast agent nephropathy following contrast agent administration
  • Comparison of plaque components in significant coronary stenoses in patients with vs. without renal insufficiency
  • Neurohumoral, haemodynamic and angiographic parameters as perioperative screening in heart surgery: Which variables prove the best predictive value?
  • Influence of polymorphisms on the restenosis rate after coronary stent implantation
  • Comparison of restenosis rate after PCI – randomized comparison of stent implantation vs. conventional PCI without stents
  • Re-opening of chronic occlusive vene grafts – long-term outcome in BMS vs. DES
  • Mortality in the acute coronary syndrome – analysis of patient-independent and coronary risk factors
  • Improvement of outcome after introducing the 24-h-PCI standby – can a reduction of primary end points be proven?
  • Factors influencing mortality in acute STEMI - analysis of regional and socioeconomic factors
  • Comparison of implementation of NSTEMI guidelines in a university clinic cardiology vs. a communal hospital – comparison of laboratory courses, times of intervention and outcome
  • Influence of rescue PCI`s in acute myocardial infarction on quality of life in patients aged ≤ 75 years vs. > 75 years
  • Analysis of MACE events in STEMI – which prognostic value has the TIMI score? 
  • Influence of inflammatory parameters and activation of coagulation system on restenosis after coronary stent implantation
  • One-year follow-up after occlusion of a persisting PFO by catheter insertion

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Electrophysiology / Rhythmology

Clinical Research Organization rhythmology
  • Ventricular tachycardia in patients suffering from left ventricular dysfunction: Influence of central and obstructive sleep apnoea syndrome 
  • Improvement of position of left ventricular pacemaker lead in cardiac resynchronisation systems by electrophysiological examinations in patients with dilated cardiomyopathy 
  • Influence of age and gender on ECG changes in the Brugada syndrome
  • Sensitivity and specificity of ECG and Body Surface Potential Mapping in the diagnosis of left ventricular hypertrophy
  • Comparison of electrocardiographic and haemodynamic parameters in different pacemaker programmings in patients with 3rd degree AV blocks
  • Pacemaker implants in babies and toddlers – indications, long-term outcomes, revisions and complications
  • Sensitivity and specificity of transesophageal echocardiography in diagnosis of endocarditis of the pacemaker lead
  • Aetiology and complications in probe extractions of cardiac pacemakers and cardioverter/defibrillator
  • Long-term evaluation of patients suffering from cardiac insufficiency undergoing cardiac resynchronisation therapy
  • Increase of neurohumoral parameters and BNP after implantation of pacemaker devices – is an implantation associated with cardial impairment?
  • Indicators for implantation of a defibrillator in patients suffering from cardiac insufficiency – how well-informed are GPs?
  • Safety and clinical usefulness of a new implantable cardioverter/defibrillator
  • Prognostic impact of ventricular arrhythmia diagnosed by long-term ECG in patients with implanted cardioverter/defibrillator
  • Risk factors for recurrence after electric cardioversion of atrial fibrallation (AF) – generation of a multivariate model and validation in a prospective study
  • Prognostic value of an a-wave after electric cardioversion
  • Predictor for successful pulmonary vein isolations in persisting AF
  • Long-term follow-up of patients with intraoperative ablation of AF – first experiences
  • Cryoablation in atrial fibrillation – a case-control study
  • Comparison of anticoagulation with NOACs vs. Marcumar in non-valvular atrial fibrillation regarding the bleeding rates and major complications – a multinational register with 2,500 patients
  • Patient characteristics, procedural parameters and acute outcomes in atrial fibrillation ablation guided by focal impulse and rotor mapping: results from the E-FIRM Registry
  • Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation with Focal Impulse and Rotor Modulation Guided Procedures
  • Questionnaire regarding the level of knowledge of the CHADS criteria in GPs and cardiologists
  • Level of knowledge regarding the CHA2DS2-VASc, HAS-BLED and new oral anticoagulants (NOAC) – a follow-up study

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Conventional Cardiology / Prevention / Basic Research

Clinical Research Organization conventional cardiology
  • Validity of the AGE-measured value in the early diagnosis of cardiovascular Events
  • Central venous oxygen saturation as predictor of cardiac function
  • Side-dependent differences of the diastolic and systolic blood pressure – comparison of invasive vs. conventional measurement
  • Case series with new omega-3 fatty acid: Compound´s influence on the lipid status in patients suffering from HLP
  • Effectiveness of lipid apheresis in patients with CHD and therapy-refractory HLP – study covering a period of 17 years
  • Successful H.E.L.P. therapy in isolated Lp(a) increase
  • Influence of an isolated LP(a) increase on the coronary status
  • Significance of hypercholesterinaemia in additional Lp(a) increase for the prevalence of CHD
  • Reference value determination of the LP(a) regarding an increased prevalence of CHD
  • Exploration of the effects caused by slightly, moderate or severe enhanced Lp(a) on coronary arteries
  • Independent clinical and laboratory chemical influences on Lp(a) - which therapeutic approaches are identifiable?
  • Significance of the Marburg-I and Marburg-II mutation on the prevalence of the CHD
  • Sensitivity and specificity of laboratory and inflammatory markers as well as of exercise tests to diagnose CHD
  • Diagnostic methods in evaluation of CAD – value of exercise electrocardiography and stress echocardiography
  • Sensitivity and specifity of Copeptin in ruling out acute myocardial infarctions
  • Implementation of new biomarkers in cardiac infarction diagnostics
  • Perioperative bridging therapy with low-molecular-weight heparin in patients with AF – a retrospective study
  • Bridging therapy with low-molecular-weight heparin in cardiac patients – a prospective multi-center study including 2000 patients
  • Correlation between PROCAM Score, body dimensions and anamnestic parameters – creation and validation of a revised score
  • Education and prevention in patients with arterial hypertension – a large national survey
  • Predictive value of ECG to identify diastolic heart failure

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Cardiac Surgery

cardiac surgery
  • Prognostic factors after aortocoronary bypass surgery in patients above the 9th decade of life
  • Predictors for the hospital mortality in cardiac surgical operations – which influence does patient´s age have? 
  • Gender-dependent risk factors for long-term mortality after operative myocardrevascularisation – an analysis including 4000 patients
  • Outcome after coronary bypass surgery – a monocentric study over a period of 8 years
  • Long-term follow-up after CABG – comparison of venous and arterial bypasses
  • Prophylaxis of atherosclerotic complications during heart operations with extracorporeal circulation through intra-aortic filters
  • Long-term outcome after heart transplantation: Mortality and incidence of transplant vasculopathies
  • Risk factors for mortality after orthotopic heart transplant – an observation study over 10 years
  • Prognostic impact of tricuspid insufficiency after heart transplantation – a long-term follow up
  • Comparison of prognoses of patients with terminal cardiac insufficiency with vs. without assist Systems
  • First-in-human pilot study to demonstrate the safety and the performance of a new cardiac therapy system
  • Intra-aortic catheter pump for decompensated heart failure - a study to obtain the CE mark
  • Prognosis after the ECMO-therapy – determinants for mortality in adult and pediatric patients
  • Outcome of patients after heart operations: CABG vs. CABG + additional mitral valve replacement
  • Outcome of patients after MKE in mitral valve endocarditis
  • Comparison of patient collective, intrahospital course and long-term course in biologic vs. mechanic endoprosthetic replacement of mitral valve
  • Influence of minimal invasive vs. conventional OP methods on laboratory parameters after heart operations
  • Dependence of the intraoperative brain perfusion in operative myocardrevascularisations by different operating procedures on-pump and off-pump
  • Thrombopeniae and other changes in the blood picture after heart-lung machine
  • Outcome after prosthetic aortic valve replacement in patients with medium vs. high-grade valvular aortic Stenosis
  • Long-term results after implantation of SJM bio prostheses
  • One-year mortality after prosthetic aortic valve replacement in over 80-year-old patients
  • Quality of life after proximal ascendens replacement – a meta-analysis
  • Long-term outcome after proximal ascendens replacement – quality of life and mortality compared to normal population
  • Therapy and prognosis of aneurysms and ectasia of the aorta ascendens – are there gender-related differences?
  • Mortality after normal vs. complicated ascendens replacement
  • Value of echocardiographic follow-up after aortic valve replacement
  • Haemodynamics and intrahospital results after elective and emergency replacement of the ascending aorta in over 80-year-old patients
  • Which statin proves to be most effective regarding prophylaxis in patients after aortic valve replacement?
  • Long-term follow-up of the SuperStentless biological aortic valve replacement 
  • Comparison of biological aortic valve prosthesis with vs. without stent
  • Comparison of HLM times and implantation times in different biological aortic valve operations
  • TAVI in biological valve prostheses (“valve-in-valve“)
  • Mortality after tricuspid reconstruction vs. tricuspid valve replacement – a prospective multicentre study
  • Risk factors for mortality in the event of an Type A acute aortic dissection
  • Importance of preoperative neurological dysfunctions in patients undergoing emergency surgery in type A dissections
  • Clinical course after operation of congenital heart diseases in babies
  • Quality of life (SF-36 and BGS98 of the RKI) of patients after arterial switch operation
  • Long-term outcome and quality of life of patients after different operating procedures in aortic aneurysms Type Stanford A
  • Surgery procedures and long term survival after surgical removal of cardiac tumours – review of consecutive cases over 20 years
  • Operationsverläufe und Langzeitüberleben nach operativer Entfernung von Herztumoren – eine Aufarbeitung von konsekutiven Fällen über 20 Jahre
  • Risk factors for wound healing disorders after heart operations – a prospective study including 800 patients
  • Predictors for renal failure after cardiac surgery
  • Prevalence of acute kidney injury after cardiac surgery – a mulitnational study
  • Incidence of renal failure in elective cardiac surgeries vs. emergency surgery
  • Short-term results and improvement of quality of life after operative catheter ablation of atrial fibrillation
  • Influencing factors on postoperative inflammatory processes after thoracic surgery – which impact have drainages?
  • Comparison of deep wound-healing after sternotomies with single wire vs. double wire technique
  • Adhesion prophylaxis after cardiac surgery – comparison of different membranes
  • Long-term follow-up after TEA of the carotis
  • Influence of age on post-operative results of carotis operations

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Vascular Surgery / Angiology

angiology
  • The distal origin bypass as treatment option in the diabetic foot ulcer
  • Long-term results after bypass in the diabetic foot syndrome – a long-term follow-up study
  • PTA versus Hybrid - OP – a prospective analysis of interventions in the femoropopliteal area. A multicenter study
  • Interventional procedures for the therapy of advanced pAVK - a review
  • Effectivity of drug-coated balloons in the interventional treatment of pAVK
  • Patency rates, major amputations and mortality after bypass graft surgery in patients with peripheral arterial disease phase IV
  • Amputations and patency rates after PTA and stenting of the lower limb
  • Perianastomotic flow profile and elasticity of vascular anastomoses
  • Duplex sonography before and after doing sports in patients with peripheral arterial disease
  • Infragenual bypass grafts – indications, risks, and long-term follow up
  • Amputation rates of the leg after different operations – a long-term study
  • Perioperative infections and outcome after implantation of Cronocol implants in the surgical treatment of patients suffering from stage III and stage IV PAD – a case series
  • Prevalence of MRSA colonization in vascular surgery and determining factors for the postoperative course
  • Increased intima media thickness of the carotis – an analysis of different ultrasonic probes and techniques as well as of interobserver variance
  • Pharmacomechanical recanalization of A. Carotis occlusions - risk factors and long-term progressions

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Pulmology and Sleep Medicine

Pulmology
  • Change of pulmonary function parameters after bronchial provocation test with different Allergens
  • Safety and effectiveness of treatment with a new beehive air therapy System
  • BNP level in different pulmonary diseases as well as associations between BNP level and FEV 1
  • Sensitivity and specificity of the ProGRP in the diagnosis of malignant pulmonary diseases with differing histology
  • Mortality in different lung tumors - a long-term survey in a university facility
  • Clinical evidence of lymph nodes in malignant pulmonary diseases – sensitivity and specificity of observed lymph node enlargement
  • Treatment of chronic malignant pleural effusions by suction drainage - clinical benefit and treatment risks
  • Quality of life in patients with alpha 1-antitrypson defiency before and after Substitution
  • Effect of different radionuclides in patients with pulmonary metastasized neuroendocrine Tumors
  • Success rates and clinical courses in different catheter-based therapies in pulmonary embolisms
  • Change of polysomnographic parameters after different therapies in patients with obstructive sleep apnoea
  • Consecutive sleep apnoea screening of risk patients – what is the prevalence of positive findings?
  • Therapeutic success in the obstructive and central sleep apnoea syndrome
  • Long-term clinical course of pulmonary function parameters in patients with chronical obstructive pulmonary diseases – a retrospective analysis over a period of 10 years
  • Prevalence of coronary heart disease in patients with chronical obstructive pulmonary diseases 
  • Improvement of vigilance and capacity of reaction by nCPAP in patients suffering from obstructive sleep apnoea syndrome
  • Influence of the non-invasive ventilation on the renal function in patients with central sleep apnoea
  • Influence of different medicinal therapies on the polysomnographic parameters in patients suffering from restless legs Syndrome
  • Treatment of insomnia with physical information medicine – a study for the preservation of CE marking
  • Influence of diseases of the cervical spine on the sleep architecture and its treatment with nCPAP
  • Comparison of drug levels and effectiveness of different antibiotics in pneumoniae

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Gastroenterology and Abdominal Surgery

Upper Gastrointestinal Tract – Oesophagus and Stomach / Endoscopy / Medical Imaging

Upper Gastrointestinal Tract
  • Retrospective study of patients with gastro-oesophageal reflux disease after laparoscopic fundoplicatio
  • Medicinal treatment of reflux oesophagitis – effectiveness in patients with vs. without HP infection
  • Treatment of gastroesophageal reflux disease by stimulation of the lower esophageal sphincter – a long-term observation of 1000 patients
  • Singing as risk factor for reflux oesophagitis – case-control study with professional singers
  • Match of endoscopic and histological results in the gastroscopy – what degree of improvement is achieved by the systematic implementation of biopsies?
  • Case series of a new procedure for the endoscopic treatment of Barrett´s oesophagus
  • Influence of radiotherapy on the 10-year-survival probability in oesophagus carcinoma
  • Determination of different coagulation parameters as predictors of a postoperative haemmorrhage after radical oesophagectomy
  • Cytokines and TNF-α in HP-positive and –negative ulcers in the duodenum and antrum
  • Prognosis and therapy of non-Hodgkin-lymphoma of the stomach – a survey
  • Risk factors for mortality in the corpus carcinoma and cardia carcinoma
  • Sedation complications during endoscopy before and after the implementation of the new S3 guideline
  • Sensitivity and specificity of different examination procedures for the early diagnosis of cystic abdominal tumors

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Lower Gastrointestinal Tract – Bowel Diseases

Lower Gastrointestinal Tract – Bowel Diseases
  • Treatment of antibiotic-associated diarrhoea
  • Antibiotic-associated diarrhoea – a follow-up study comparing the effect of Actimel vs. Yakult
  • Treatment effect of probiotics in clostridium difficile associated diarrhoea (CDAD)
  • Risk factors and patient clientele for antibiotic-associated diarrhoea
  • Different forms of gastroenteritis within one year in a community hospital – germ spectrum, clinical symptomatology and antibiotic treatment
  • Long-term clinical course and complications in patients with chronic inflammatory bowel diseases
  • Changes in diagnostics, symptomolgy and treatment of patients with inflammatory bowel diseases between1995 and 2010
  • Life-quality in patients with chronic inflammatory bowel diseases with conservative vs. surgical therapy – SF36 and validation of a new scor
  • Influence of primary sclerosing cholangitis on chronic inflammatory bowel diseases
  • Prognostic value of FXIII in inflammatory bowel disease
  • Clinical symptoms and endoscopic results in patients with Crohn´s disease
  • Surgical procedures to treat chronic inflammatory bowel diseases
  • Validation of different tumor markers to diagnose malignant and inflammatory bowel diseases
  • Risk factors, histological results and course of disease in complicated appendicitis
  • Clinical symptoms and treatments of the postinfectious irratible bowel syndrome after journeys to tropical and subtropical regions – an interdisciplinary long-term study
  • Mental and physical quality of life in postinfectious irritable bowel syndrome
  • Comparison of the effectiveness of therapies in patients with fructose intolerance or lactose intolerance
  • Variability, validity and examination dependence measurements by rectoscopy
  • Does the number of dissected lymph nodes have any influence on the diagnosis of the colon carcinoma? Quality assurance
  • Survival of peritonectomy and hyperthermic intraperitoneal chemotherapy in the colon carcinoma
  • Treatment of chronic ascites by suction drainage - clinical benefits and treatment risks
  • Adenoma-carcinoma-sequences in different adenomas and carcinomas of the bowel
  • Sensitivity and specificity of the MRI and endosonography in the diagnosis of the rectal carcinoma
  • Lymph node staging as predictor for long-term survival in the rectal carcinoma
  • Comparison of outcome in different surgical methods in the rectal carcinoma
  • Improvement of guideline conformity after having qualified as centre for intestinal medicine in the treatment of the rectal carcinoma
  • Validity of the MRI in the diagnosis of the familial adenomatous polyposis (FAP)
  • Long-term outcome in patients with rectal carcinoma – comparison of laparoscopic vs. open rectum resection
  • Anastomotic leaks after surgical restructuring of rectal and colon carcinoma: Analysis of risk factors, inflammation parameters and mortality
  • Comparison of the SILS technique vs. conventional multiport techniques in laparoscopic sigma resections
  • Carrying out intraperitoneal chemotherapy in peritoneal metastasising abdominal tumours or mesotheliomae – a case series
  • Hepatic dysfunctions after intraperitoneal administration of chemotherapeutics in peritoneal carcinosis
  • Comparison of the quality of life (SF-12) in different intraabdominal and extraabdominal tumors
  • Prognostic value of PET in gastrointestinal tumors  
  • Treatment of patients with peritoneal carcinosis: thermic courses and periprocedural courses when carrying out an intraperitoneal chemotherapy

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Hepatology / Diseases of the Pancreas

Hepatology / Diseases of the Pancreas
  • Validation of new tumor markers in malignant hepatic diseases
  • Outcome in patients with hepatocellular carcinoma treated with different therapies
  • Clinical and histologic results after carrying out of ALPPS procedure (Associating Liver Partitionn and Portal Vein Ligation for Staged Hepatectomy) in patients with primary and secondary malignoma of the liver
  • Clinical course of hepatic enzymes after different surgical procedures in patients with different hepatic diseases
  • Influence of interferon treatment in different dosages on the long-term clinical course in patients with hepatitis C
  • Change of different hepatic enzymes under different alternative treatment strategies in patients suffering from hepatitis C
  • Diagnostics and therapy of hepatitis C in GP care
  • Long-term studies in patients with hepatitis C, where a sustained virological response (SVR) was diagnosed – study covering a period of 8 years
  • Therapy options in hepatitis C: Responder and non-responder in different genotypes
  • Liver enzymes and clinical procedures in hepatitis E
  • Early diagnosis of cognitive underperformance in chronic alcohol adiction
  • Sensitivity and specifity of different external- and self-assessment scales in the diagnosis of hepatic encephalopathy
  • Monocentric experiences in transjugular intrahepatic portosystemic shunts
  • Influencing factors in the post-interventional pressure gradients after applying intrahepatic portosystemic shunts – a follow-up study
  • Hepathic encephalopathy and other complications of the Liver-Ci with vs. without TIPS portal
  • Influence of alcohol abuse on the production of mRNA of the POMC before and after CRH administration as well as after stress tests
  • Monitoring of patients after hepatic transplantation – clinical implementation of biochemical markers. a long-term Analysis
  • Mortality and recurring cirrhosis after liver transplantations
  • Survival analysis of patients with polytrauma and liver injuries – comparison of different forms of treatment
  • Laser treatment in patients suffering from inoperable hepatocarcinoma – influencing variables on the extent of necrosis
  • Liver function reading as early marker of a rejection reaction after orthotopic liver transplant
  • Mortality of patients on a waiting list before orthotopic liver transplant
  • Comparison of sensitivity of the sonography and the CT scan in gall stones and bile duct stones
  • Prognostic value of different ultrasound systems to diagnose gallstones
  • Risk factors for complications after cholecystectomies
  • Acupuncture as a means of pain relief after cholecystectomies
  • Prognostic impact of different chemotherapies in patients with pancreas carcinoma
  • Familial clustering of the pancreas carcinoma as well as the incidence of secondary occuring tumors
  • Substitution of pancraes enzymes in chronic pancreas insufficiency
  • Influence of spontaneous bacterial peritonitis on liver function reading and retention value – long-term surveys and overall prognosis

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Abdominal Surgery

Abdominal Surgery
  • Carried out abdominal surgery in the last 20 years – modifications of the types of operations and techniques as well as reduction of length of stay
  • Patient registry for robotic assisted laparoscopic procedures in abdominal surgery
  • Change in age structure and the ASA stage in abdominal surgery
  • Risk factors for seroma after abdominoplasty considering different surgical methods
  • Prophylactic use of synthetic nets in abdominal surgery to avoid incisional hernia
  • Incisional hernia prophylaxis after stoma reversal surgery - a challenge for surgery - presentation of the early-postoperative course of two patient groups
  • The early postoperative course after colostomy reversal surgery with prophylactic tissue reinforcement reconstruction of the abdominal wall. A comparison study of two tissue reinforcement products – GORE®BIO-A® versus DynaMesh®-CICAT
  • Risk factors for the development of incisional hernia after abdominal operations
  • Comparison of different treatment strategies of anastomoses insufficiencies after resecting surgery in carcinoma of the upper gastrointestinal tract
  • Risk factors for colon ischemia after the operations of aortic aneurysms carried out in emergencies
  • Acute mesenteric ischemia after cardiac surgery - incidence, risk factors and prognosis
  • Prognostic value of the I-FABP in mesentric ischemia and after heart surgery with HLM
  • Comparison of predictive values of SAPS II, APACHE and DELAWARE after abdominal surgery
  • Seroma formation after abdominoplasty with different surgery techniques
  • Risk factors for superficial and deep post-operative wound-healing disorders
  • Improvement of post-operative outcome in bariatric surgery by interdisciplinary cooperation
  • Mortality, disseminated intravascular coagulation and infections within 30 days after total or partial splenectomy
  • Risk factors of burst abdomen after different surgeries

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Endocrinology

endocrinology
  • Correlation of different antibodies with the grade of malignancy in neuroendocrine tumors of the gastrointestinal tract
  • Apoptosis of euthyroid thyroid gland tissue: influence of implemented substances and solvents on cell growth
  • Risk factors for the occurence of autoimmunthyreoiditis in patients with vegetarian or vegan nutrition – which role does the iodine/selenium quotient play?
  • In vitro study: apoptosis under various trial conditions
  • Modifications of renitency and haemodynamic parameters in patients with primary hyperparathyroidism
  • Influence of hyperparathyroidism on hepatic and renal function
  • Success rates of different surgery methods in hyperparathyroidism
  • Risk factors for the development of recurring goiter and its therapy
  • Recurrences and mortality after surgical treatment of thyroid Tumors
  • Risk factors for recurrence paresis after thyroid surgery – a multicenter study
  • Post-operative haemorrhages, wound infections and recurrence paresis after strumectomies in struma multinodosa
  • Influence of age on recurrent paresis after strumectomy
  • Outcome in patients with metastasising neuroendocrine tumors under different therapy procedures
  • Sensitivity and specifity of different diagnostics for the differentiation of diagnoses and differentiation of neuroendocrine tumours

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Diabetology

Clinical Research Organisation Diabetes mellitus
  • User evaluation of a new insulin pump system under everyday conditions
  • Non-interventional study with a new Insulin pump
  • Performance of a new insulin pump in routine care of adults and adolescents with type 1 diabetes: Effectiveness and Safety of a touch screen based insulin infusion pump in a non-interventional Study
  • Comparison of the efficacy of sensor-augmented pump therapy versus hybrid closed-loop glucose management in patients with type 1 diabetes at home.
  • Comparison of HbA1c and growth in children with type 1 diabetes with vs. without migration background
  • Addressing the fear of hypoglycemia in children with type 1 Diabetes
  • Case series with a new antidiabetic agent: Influence on glucose metabolism in patients suffering from type 2 diabetes mellitus
  • Epidemiologic data, therapy and course of disease in patients with type 2 diabetes – a retrospective survey covering 15 years
  • Diabetes-screening in dental practice using the Find-Risk questionnaire – a practice based pilot study
  • Reduced health care costs with automated basal insulin titration in patients with type 2 diabetes
  • Reduced utilisation of health care provider resources with automated basal insulin titration in patients with type 2 Diabetes
  • Life-quality in diabetes mellitus after training with different sport Programmes
  • Influence of sportive activity in normobaric hypoxia on glucose metabolism in patients suffering from type 2 diabetes mellitus
  • Sources of information for patients with type 2 diabetes mellitus – of what importance is the internet?  
  • Sensitivity and specificity of albumin rapid tests in patients suffering from diabetes mellitus
  • Risk factors for albuminuria – what influence do metabolic factors have?
  • Long-term predictors for amputations in patients suffering from diabetic foot

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Rheumatology

rheumatology
  • Detection of antinuclear antibodies in connective tissue diseases and acute inflammatory illnesses – a consecutive study with extensive laboratory examinations in a large communal hospital
  • Non-responder of MTX therapy in juvenile idiopathic arthritis
  • Effectiveness of infliximab biosimilar for inhibiting inflammation and reducing functional limitations in rheumatoid arthritis - a multicenter study
  • Therapeutical effect of intraarticular injection in idiopathic polyarthritis
  • Clinical symptoms in fibromyalgia – a multicenter study
  • Risk factors for soft tissue infection after surgeries in patients with rheumatic arthritis
  • Improvement of symptoms and quality of life before after various therapies in patients with rheumatic arthritis (application of EQ-5D-5L and several VAS)
  • Quality of life and restriction of performance in patients with rheumatic arthritis
  • Outcome after treatment with biologicals and MTX in patients with rheumatic diseases
  • Sensitivity and specifity of ß-catenin in diagnosis of arthrofibrosis
  • Association between MMP-8 and rheumatic arthritis
  • Influence of rheumatism on periodontitis - an interdisciplinary study

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Nephrology

urology
  • Comparison of the therapy of renal artery stenoses: PTA vs. surgery
  • Diagnostics and therapy of the complicated renal cyst
  • Comparison of different calculation methods of the creatinine clearance and analysis of related error sources
  • Comparison of measured vs. calculated glomerular filtration rate – evaluation of a gold standard
  • Influence of Aquaporin 1364AC polymorphism on renal function in patients with ARDS
  • Risk factors for contrast agent nephropathy as well as the effectivity of protective substances
  • Preparedness to donate organs – Survey of the Federal Centre for Health Education and the Essen University
  • Clinical influencing factors on transplant survival after NTx
  • Renal perfusion values and retention values in acute rejection after renal transplatation
  • Long-term survey of renal function after kidney transplantation
  • Biomarker to optimize immunosuppressive therapy after NTx
  • Predictive values for functional deterioration and rejections after kidney transplants
  • Medication compliance after kidney transplantation – long-term survey
  • Prevalence of acute kidney injury after cardiac surgery – a mulitnational study
  • Validation of Fetuin A as surrogate parameter in patients with chronic dialysi
  • Comorbidities and long-term surveys of patients suffering from dialysis-dependent renal insufficiency
  • Perioperative risks in patients with advanced renal cell carcinoma
  • Germ spectrum as well as evidence of MRSA in dialysis centres
  • Influence of special diet in dialysis patients on muscle power and nutritional status

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Urology

Clinical Research Organization Urology
  • Epidemiology of MRSA-infected patients in a urologic University Clinic – an analysis over a period of 15 years
  • Prostate carcinoma: comparison of conventional and new procedures to determine prostate volume before and after therapy
  • Prognostic determinants of recurrence and survival in prostate carcinoma
  • Long-term prognosis of patients with early recurrence after R0N0 prostatectomy      
  • Influencing factors on the extraction quality of histological specimens in prostate carcinoma – an analysis with 38.000 specimens
  • Treatment of prostate carcinoma with Doxetaxel – long-term prognoses and treatment costs
  • Avoiding progression of the prostate carcinoma by brachytherapy – long-term survey
  • Effects and side-effects of the Seed therapy in patients suffering from prostate carcinoma
  • MR imaging-ultrasound fusion in prostate carcinoma
  • Long-term results after photoselective valporisation of the prostate – a multicentre study
  • Sensitivity and specificity of prostate biopsy in different localizations
  • Assessment of the prognosis from prostatectomy specimens and postoperative re-evaluation of operation indication
  • Application of the HybridKnife in the urothelial carcinoma – a multicentre study
  • Long-term results after oral mucoplasty in urethral stricture        
  • Sensitivity and specifity of the diagnosis of the urothelial carcinoma by histologic and cytologic procedures
  • Outcome after cystectomy in the urothelial carcinoma – prognostic determinants at different stages in life
  • Validation of a micturition protocol in patients with overactive bladder
  • Influence of hysterectomies on the frequency of atone voiding disorders
  • Comparison of different therapies in erectile dysfunction
  • Xanthine oxidase as risk factor for erectile dysfuncion
  • Analysis of independent risk factors for erectile dysfunction taking into account pulse wave velocity as a determinant of vascular stiffness
  • Therapy outcomes of erectile dysfunction in patients with different clinical and laboratory chemical risk profiles
  • Medical evidence of different antibodies in children with recurring urinary tract infection
  • Effects of polymorphisms on the incidence of urinary tract infections

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Oncology

oncology
  • Tolerance of different chemotherapeutic substances in the colon carcinoma – a case series
  • Prognostic factors in the multiple myeloma
  • Case series in patients with multiple myeloma – effectiveness of Caphosol®
  • Outcome and prognostic parameters in patients suffering from neuroendocrine tumors
  • Improvement of diagnostics and therapy by an interdisciplinary conference in tumor patients
  • Mortality in fungal pneumonia after bone marrow transplant
  • Generating of t-lymphocytes for the immune therapy after stem cell transplantation
  • Effectiveness of mouthwash solutions in children suffering from leukaemia
  • Palliative therapy in patients suffering from colon carcinoma – case series with several chemotherapeutic substances
  • Implementation of the g-CSF prophylaxis to avoid neutropenia in malignant lymphoma
  • Parenteral nutrition in outpatient oncologic care: Standardised three-chamber bags vs. patient-individual preparation
  • New chemotherapies in patients suffering MDS and AML
  • Trabectedin as first-line-therapy in soft tissue sarcomae

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Traumatology / Emergency Surgery / Orthopedics

Upper Limb

upper limb
  • Comparison of long-term results and capacity after radial fractures as well as comparison of different evaluation scores
  • Decrease of hand force in patients after radial fractures, carpal tunnel syndrome or arthrosis
  • Nerve compression syndrome after surgical treatment of carpal tunnel syndromes – comparison of two surgical methods
  • Influence of type of fracture, age and sex on the pronation and supination force after radial fractures
  • Quality of life and functionality after wrist arthroscopy in type 1a lesions of the TFCC
  • Long-term prognosis after surgically treated scaphoid fractures
  • Interobserver reliability of CT scan in the plane of wrist versus in the long axis in scaphoid fractures
  • Force measurement by means of Jamar after phalanges fracture – what is the therapeutic success of different therapy strategies?
  • Quality of life after upper arm fractures – comparison of different scores
  • Influence of dorsal plate osteosynthesis on the thumb extension function and wrist mobility
  • Impact of tendinosis calcarea on mobility of shoulder joint 
  • Implementation of DASH Score in burns in the area of the upper pectoral girdle
  • Long-term effects after different surgical treatments of acromioclavicular separation – what is the significance of the DASH Score?
  • Experiences with plexus anaesthesia in shoulder operations

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Trunk / Spine

spine
  • Sensitivity and specifity of clinical results vs. MRT scores in patients with rheumatic arthritis
  • Comparison of long term follow-up after laminectomy vs. laminotomy
  • Treatment of degenerative lumbar spine diseases by cage implantation– a case series
  • Effectiveness of conservative therapeutic methods in the treatment of osteochondrosis pain 
  • Improvement of mobility and quality of life after implantation of intervertebral discs prostheses in advanced kyphoscoliosis
  • Long-term results after implantation of intervertebral discs prostheses in kyphoscoliosis
  • Long-term follow up after surgery of dorsal spondylodesis in patients with adolescent idiopathic scoliosis – results ot treatment with rigid braces
  • Comparison of different intervertebral discs prostheses
  • Kyphoscoliosis angular, compression index and pain after kyphoplastic – a follow-up study
  • Diagnostic value of nuchal reflex zones in dysfunction of the cervical spine
  • Comparison of hyperthermia vs. acupuncture refering to pain and quality of life in patients with chronic back pain
  • Ache and limitation of movements of the cervical spine triggered by sitting occupations – positive influence caused by Biofeedback
  • Comparison of different surgery procedures of the facet joints of the cervical spine
  • Clinical and radiologic results after facet denervations
  • Vergleich verschiedener Operationsverfahren der Facettengelenke der HWS
  • Klinische und radiologische Ergebnisse nach Facettendenervierungen
  • Long-term follow up after surgery of scoliosis – comparison of two operation methods
  • Pelvis torsions caused by differences in leg length – a pilot study with 3D measurements of the spine
  • Quality of life in patients with chronic back pain (ICD-10 symptom rating, Regensburger back arch questionnaire, scales to measure quality of life)
  • Validation of screening questionnaires for the differentiation of organic vs. psychosomatic back pain

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Lower Limb

lower limb
  • Comparison of pain and mobility of the big toe joint in rheumatic patients with endoprothetic surgeries
  • Quality of life and functional outcome after operative stabilisation of fractures of the pelvic ring
  • Follow-up after arthroscopic discus resection in traumatic discus lesion
  • Arthroscopic treatment of cartilage damages of the knee with collagen
  • Follow-up after partial meniscectomy in medial meniscal tears
  • Improvement of functionality and quality of life (SF-36, Lysholm and VAS) BY growth factors in degenerative cartilage defects of the knee joints
  • Outcome after administration of tranexamic acid in knee joint surgeries
  • Significance of different radiologic procedures for the positioning of the drill channel in the anterior cruciate ligament reconstruction – a multi-center study
  • Radiologic signs in different histologic forms of haemangioma of the knee
  • Predictive values of the new screening of dysplasia of the hip joint in newborns
  • Post-operative progress after TEP in patients with severe osteoarthritis of the hip
  • Follow-up of the lateral access (Bauer) in prosthetics
  • Prospective study for the evaluation of the functional outcome and the osteointegration after total endoprosthesis
  • Influence of time from admission to surgery for medial femoral neck fracture on patient prognosis - is compliance with the 24-hour interval overestimated?
  • Patients with proximal femoral fracture and contralateral fracture during the course - risk analysis and independent determinants
  • Influence of wound infections and hematomas after surgery of proximal femoral fractures on mortality
  • Range of movement and mobility after hip joint replacement – a matched pair analysis
  • TEP implantation after fracture of the femoral neck in patients > 75years of age: Comparison of cemented vs. uncemented prosthese
  • Infections, revisions and mortality in patients with proximal femoral fracture - Comparison of surgical treatment with a proximal femoral nail vs. dynamic hip screw
  • 10-year survival after proximal femoral fracture and after surgical treatment with osteosynthesis vs. endoprosthesis
  • Long-term prognosis after implanting of cemented total endoprotheses
  • Long-term prognosis after implanting of uncemented total endoprotheses
  • Revision rates and mortality after TEP implants in patients older than 90 years of age
  • Estimated and calculated blood loss in endoprosthetic hip replacement
  • Quality of life of patients after implantation of a Wagner prosthesis
  • Performance and quality of life after total endoprostheses - how important is the Staffelstein score?
  • Comparison of functionality of the hip after different surgical accesses in resurfacing
  • Comparison of methods by goniometer and kinect to measure active joint mobility in patients after TEP
  • Objective and subjective progress after lateral accesses in the resurfacing – progress of the Harris-Hip scores and the Womac sum scores
  • Quality of life after implantation of a dual head prosthethis in patients > 85 years of age
  • Mortality, mobility and quality of life in patients > 85 years of age after TEP implants – a long-term evaluation
  • Revisions of a hip TEP due to loosening or due to fracture of the femur along an embedded prosthesis – comparison of progress in different Vancouver classes
  • Influencing factors on mortality and revision after reconstruction of periprosthetic femur fractures
  • Analysis of metal ions in serum and urine after TEP operations
  • Biomechanical results after modified PEMBER-SAL acetabuloplasty for the treatment of congenital hip dysplasia and perthes disease
  • Influence of homocysteine on the incidence of pathologic fractures
  • Follow-ups after fractures of the processus calcaneus
  • Extent and pain as well as reduction of mobility due to calcaneal spur
  • Long-term courses over 20 years after calcaneal fractures – functionality, pain and quality of life
  • Comparison of dynamic and fixed after-care of surgically treated malleolar fractures in a vacuum-stabilized orthesis – a randomized controlled monocentric study
  • Measuring of the angle in the hallux valgus – comparison of different measuring techniques
  • Long-term bleeding after surgical treatment of Achilles tendon ruptures with various suture techniques
  • Infection rate after dual head prosthethis – comparison of different treatment strategies
  • Comparison of results of manual vs. navigated knee joint prosthesis
  • Interventional Study with a new knee endoprothesis to obtain the CE mark
  • Follow-ups after secondary retropatellar replacement – a meta-analysis
  • Knee joint prostheses in symptomatic osteoarthritis: Mobility, symptoms and scoring systems before surgery and follow-up
  • Comparison of functionality after replacement of the posterior cruciate ligament vs. external ligament reconstruction according to Larsen - a randomized study
  • 10-year follow-up after autologous chondrocytes transfer in the knee Joint
  • Long-term courses after arthrodesis of the knee joint – comparison of results of intramedullary nails vs. plate arthrodesis
  • Segment transport with the Iliazarov method – a prospective analysis with 218 patients
  • Comparison of several radiologic procedures in the planning of hip prostheses – which method is the most exact?
  • Gait analysis for various diseases of the ankle, knee and hip joint including analysis of the healthy side
  • Anteroposterior tibial tendon transfers as a method in treatment of peroneal paralysis

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Aesthetic Medicine / Plastic Surgery

  • Reduction of the subcutaneous adipose tissue through application of lipolytic agents
  • Weight reduction in obesitas caused by new drugs – a case series
  • Weight reduction through application of new medical substances – a long term follow-up study
  • Risk factors for thromboembolic events in plastic surgery
  • Morphologic and aesthetic limitations of different bone marrow transplantations in reconstructive plastic surgery
  • Outcome nach Verbrennungsunfällen mit einer Verbrennungsfläche > 30%
  • Lebensqualität nach Verbrennungen – eine Langzeitstudie
  • Risk factors for male gynaecomastia (1)
  • Does Hair Transplantation Restore or Improve Physical and Mental Health?   

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Anaesthesia and Emergency Medicine

Anaesthesia
  • Mortality after burn accidents in males and females
  • Influence of smoking on complication rates after accidents with polyraumata
  • Comparison of different larynx masks vs. endotracheal intubation – a case series
  • Comparison of complication rates in the use of LMA Classic vs. LMA Proseal – Experiences in a maximum care hospital
  • Case series with LMA Supreme II – a multicenter study
  • Case series with LMA MK II – a multicenter study
  • Case series with LMA Classic Excel – a multicenter study
  • Case series with larynx masks in children – a multicenter study
  • Comparison of courses of intubation in MacIntosh vs. Glideoscope – a prospective study in patients with BMI > 30
  • The complicated intubation – anatomic predictors and conception of a preoperative risk score
  • Anaesthesia-related surgery complications and mortality in children – a multi-centre analysis with 90.000 cases
  • Anaesthesia-related breathing complications after elective operations – incidence and risk factors
  • Establishing of a structured concept for the weaning from mechanical ventilation in neurosurgical patients
  • Variations of coagulation parameters through phytopharmaceuticals and potential impact on bleeding after elective surgeries
  • Alterations of vital parameters depending on depth of anaesthesia
  • Influence of fentanyl vs. ketamine-S on the postoperative intestinal motility as well as on the Ramsay Score
  • Quality of life and pain reduction with a new fentanyl patch – a multicenter study
  • Change of intrathoracic blood volume during different forms of anaesthesia
  • Comparison of progress of anaesthesia when using different relaxants
  • Drops in oxygen saturation during elective surgery depending on type and dosage of anaesthetics and patient characteristics
  • Determinants of hypoxaemia intraoperative and in the early postoperative phase – a multi-center study
  • Treatment outcome in patients with chronic pains due to interdisciplinary cooperation
  • Acupuncture procedures to reduce pain medication after inguinal hernia operations
  • Predictive values regarding mortality of laboratory parameters and scores (APACHE, SAPS, SOFA) of patients on the intensive care ward
  • Comparison of the predictive value of the APACHE score and clinical parameters of patients suffering from polytraumata
  • Influence of age on the progresses after accident traumata and on the intrahospital mortality
  • Modification of micro-circulation through pentaglobin in patients suffering from Sepsis
  • Fentanyl administration in treatment of terminally ill tumor patients
  • Comparison of the therapeutic effect of several pain medications in minimally invasive hip prosthetics
  • Therapeutic effect of the cold chamber in patients with chronic thoracic and lumbar spine syndromes
  • Postoperative satisfaction of patients with different forms of pain treatment – analysis of effectiveness of clinically applied pain therapies
  • NTproBNP as predictor of peri-operative mortality?
  • Influence of polytraumata on coagulation and inflammation parameter
  • Comparison of different heating systems to warm up accident victims – a prospective study with healthy test people
  • Comparison of further heating systems to warm up accident victims – a follow-up
  • Cardiopulmonary reanimations during ambulance service – duration of journey, location of emergency intervention and other determinants of reanimation success
  • Emergency doctors´ and paramedics´ stress coping strategies before and after emergency psychological training
  • Frequency and risk factors for outbursts of violence against doctors and nursing staff in emergency wards

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Gynaecology and Obstetrics

Gynaecology

Gynaecology
  • Comparison of histological results after ovum transplantation
  • Forced sterilisation between 1932 – 1940 – Description of operation techniques, sociocultural factors and patient population
  • Comparison of applied therapy procedures in the premenstrual syndrome
  • Risk factors for male gynaecomastia (2)
  • Releasing factors in development of male gynaecomastia
  • Establishment of new tumor markers in patients suffering from breast carcinoma in the clinical routine
  • Sensitivity and specificity of thermography in the diagnosis of breast carcinoma
  • Comparison of sensitivity and specificity of thermography in the diagnosis of breast carcinoma – a follow up study
  • Predictive values of the tomosynthesis as a screening method of mamma carcinoma
  • Sensitivity and specificity of expression of M2-PK, pAKt, ER and PR in breast carcinoma
  • Application of the MRT in breast carcinoma with different histological types – significance of the relative water content in the tissue
  • Survival analysis of patients suffering from breast carcinoma
  • Outcome in patients with triple negative breast carcinoma
  • Sensitivity and specificity of thermography in breast carcinoma – comparison of prognostic validity in comparison to the mammography – a follow up study
  • Micro and macrocalcification in patients with benign vs. malign breast tumors – diagnostic validity of mammographies
  • Prognostic value of fine granular and coarse granular calcium regarding the mamma carcinoma.
  • Prevalence and predictive values of calcium deposits regarding the mamma carcinoma in patients above, respectively below the age of 70
  • Comparison of methods to determine volume of mammae – scan vs. difference method vs. displacement method
  • HADS-Score and course of cortisol levels in the advanced breast carcinoma
  • Comparison of adjuvant therapies in metastasized breast carcinoma – influence on symptoms and quality of life
  • Influence of alternative treatment on the quality of life in the metastasizing mamma carcinoma
  • Triggering factors in the development of male gynaecomastia
  • Cytological results in preventive examinations – analysis of 7000 cases
  • Biomarkers and prognostic factors as well as therapy-dependent outcome in patients with triple negative breast cancer
  • Survival and axillary recurrence following sentinel node- positive breast cancer without completion axillary lymph node dissection
  • Validation of new tumor markers in ovarian cancer
  • Mortality and progress in ovarian carcinoma – predictive values of the CA 125
  • Validation of new tumor markers in uterine cancer regarding screening and as long-term prognostic parameters
  • Influence of operation procedure and preoperative hormone levels on the recurrence rate and mortality in uterine cancer
  • Comparison of the outcome in uterine cancer in patients with vs. without radiotherapy – in which stages does the radiotherapy show a benefit?
  • Evaluation of anxiety and depression by means of the HADS scale in the cervical carcinoma – how do different therapies influence anxiety and depression?
  • Cytological results in preventive examinations of women – a consecutive long-term study over a period of 10 years
  • Sensitivity and specificity of cytological preventive examinations
  • Influencing factors on LSIL in long term follow-up
  • Sensitivity and specifity of cytologic screenings in gynecologic practice
  • Predictive value in High Risk HPV in different cytological results
  • Incidence of pathologic HPV results during pregnancy
  • Prognostic validity of Papanicolaou IIID in smear preparations – long-term course
  • Risk factors for a descensus of the uterus as well as postoperative prognosis factors
  • Long-term course and sexuality after surgical treatment of descensus uteri
  • Incontinence after hysterectomy – risk factors, treatment and course
  • Predisposing factors for anterior, medial and posterior compartment insufficiency after hysterectomies
  • Pain after hysterectomies after preservation of a pneuomoperitoneum – comparison of different surgical methods
  • Comparison of hysterectomy in two time intervals – Changes in operation techniques, patient clientele and postoperative processes
  • Influence of climacteric symptoms on quality of life (MRS II, EORTC)
  • Dyspareunia after abdominal and gynaecological operations - prevalence, causes and impairment of quality of life

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Obstetrics

Obstetrics
  • Risk factors for high grade perineal tears during birth
  • Complication through epidural anaesthesia in nullipara, primipara and mulipara
  • High-risk deliveries with Caeserian section: Prevalence, change in management in the last 20 years as well as identification of risk factors
  • Influencing factors on the success rate in infertility treatment
  • Comparison of success of different therapies in women wanting to become pregnant as well as sensitivity and specificity of different markers for an early diagnosis of pregnancy
  • Polymorphisms of the coagulation system as risk factors for habitual miscarriages
  • Risk factors for stillbirths and abortions – analysis of regional differences and socio-economic factors
  • Level of knowledge of practising gynecologists regarding risks and prevention of pre-eclampsia
  • Prognostic importance of the tryptophan level in preeclampsia and HELLP
  • IDO as marker of placental insufficiency
  • Influence of interleukines and microbiologic diagnosis on premature birth
  • Fibronectin and other laboratory markers as test for risk evaluation of premature birth
  • Habitual miscarriages without and with treatment of low molecular heparin
  • Comparison of different therapy procedures with low molecular heparin in treating patients with habitual miscarriages
  • Improvement of miscarriage-rate in patients with habitual miscarriages by administration of low molecular heparin – a retrospective analysis of the second treatment
  • Validation of a new measurement method of endothelial dysfunction for the early diagnose of pregnant patients with pre-eclampsia
  • Mutations of the MMP2, 7 and 9 as well as GPX5 and NOX5 and expression of housekeeping genes in the placenta
  • Wound scores and sensitivity of the post-partum mastitis in different therapy approaches
  • Analysis of breastfeeding behaviour of mothers from different cultural hearths

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Ophthalmology

Ophthalmology
  • Improvement of visual acuity after implantation of new lenses – first clinical experiences
  • Case series with the lense 49CS
  • Comparison of two new lenses regarding improvement of visual acuity, complication rates and patient satisfaction
  • Comparison of cataract frequency after implantation of a posterior chamber lense in combination with an anterior vitrectomy vs. buttonhole lense implantation
  • Long-term observation of the primary open angle glaucoma – success in conservative vs. surgical treatment
  • Reliability and validity of visual acuity determination using ACTO paper eye tests
  • Visual acuity determination by ACTO eye tests in multi-morbid patients
  • The influence of refractive errors on IOP measurement by rebound tonometry and Goldmann applanation tonometry
  • Comparison of long-term results after different glaucoma surgery techniques
  • Results after surgical correction in convergent squint
  • Prevalence of squint in school children
  • Long-term results after refractive surgery
  • Long-term results after glaucoma surgery - long-term results in different medical and surgical treatments
  • Influence of analgosedation on the results in ophthalmology surgery – comparison of endotracheal intubation vs. larynx mask. Is there a gold standard?
  • Comparison of different surgery procedures in the glaucoma – risks and one-year results
  • Results of refixation after retinal detachment
  • pH-value of the corneal after different treatments in patients suffering from chemical burns
  • Influence of age and different methods of measurement on the corneal diameter
  • Clinical procedures after dilatation of lacrimal ducts
  • Patient satisfaction after transcutaneous lacrimal duct surgery in dacriocystitis
  • Association between ophthalmological vein thrombosis respectively artery occlusion and sleep apnea syndrome
  • Organ culture of deep stromal lamellated corneals
  • Influence of the yeast product on basal cell-physiologic functions of HaCaT – keratinocytes
  • Prognostic parameters regarding metastasising choroidal melanoma – comparison of symptoms and outcome under different chemotherapies
  • Arterial and venous constriction after administration of eye drops in hypertensive vs. normotensive patients
  • Epidemiologic coherencies between the „dry eye“ and the helicobacter pylori infection
  • Quality of life and resilience before and after treatment of hemifacial spasms
  • Frequency of implementation of guidelines in ophthalmological patients

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Otorhinolaryngology

Otorhinolaryngology
  • Case series with a new nasal spray: first results in clinical practise
  • Comparison of 2 divergent types of nasal sprays – differences in effects and side effects – analysis by means of a cross-over-design
  • Impaired nasal breathing due to swollen mucosae and treatment success due to acupuncture
  • Comparison of expression of angiogenesis factors in the glandula parotis, glandulae submandibularis and sublingualis
  • Comparison of results of different surgical strategies in the papilloma inverted of the nose
  • Prognosis after brachytherapy in sinonasal tumour diseases
  • Comparison of different aerosoles for the treatment of chronic rhinosinusitis
  • Effects of anticoalgulation on the incidence of Epistaxis
  • Association between cardiovascular risk factors and the carotis intima thickness on epistaxis
  • Risk factors for the development of leucoplacia and squamous cell carcinoma of the paranasal sinuses
  • Carcinoma of paranasal sinuses – risk factors, treatment and mortality
  • Prognostic relevance of different antigens in the larynx carcinoma
  • Comparison of surgical therapies of the papilloma inverted of the nose and paranasal sinuses
  • 5-year-survival of patients suffering from inoperable squamous cell carcinomas in the head-neck area after the carrying out of a hyperfractionated-accelerated radiotherapy
  • Prognostic importance of new markers in malign tumours of the oral cavity and the larynx – of what significance is the flow cytometry?
  • Long-term survival after larynx resection – influence of VEGF on clinical course and prognosis
  • Influence of the HPV in the development of squamous cell carcinomas
  • Vocal folds surfaces in polypuses, Reineke oedema, papilloma and other benign diseases
  • Typecast of unclear lymphadenopathies in ENT physicians´ practice
  • Case series: Establishing a new hearing aid – which successes can be achieved due to adjustment on both sides?
  • Hearing ability before and after surgical reconstruction with tympanoplasty, I, II – V and stapes surgery
  • Comparison of hearing ability after use of different cochlear implants
  • Influence of different rehabilitation programmes on the hearing ability after cochlear implants
  • Audiogram and speech comprehension of adolescent patients after cochlear implant implantation
  • Cochlear implants in adults who lose their hearing prelingually
  • Hearing defects in the Churg-Strauss syndrome
  • Effects of noise annoyance during operations on the operating surgeon
  • Triggering of nystagmus due to physiological stimuli in healthy test people – which influence causes the strongest nystagmus?
  • Nystagmus caused by different triggers and their treatment
  • Effects of tongue piercings on articulation

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Paedriatrics 

paedriatrics
  • Long-term course of SDS and BMI in adipose adolescents with vs. without fat-modified nutritio
  • Tracing of catch-up growth for `small for gestational age (SGA)´ children
  • Influencing factors of catch-up growth for `small for gestational age (SGA)´children
  • Influence of severity of the adrenogenitale syndrome on size and weight at birth
  • Phenotyping of the Ullrich-Turner syndrome
  • Psycho-social influences of traumatic births on the child´s development
  • Analysis of epidemiologic factors as well as educational background of parents on the development of language disorders in children and adolescents at different age-levels
  • Emergencies in newborns – information level of doctors and nurses before and after trainings
  • Foreign body aspiration in infants and toddlers
  • Comparison of the concentration of free radicals in the serum in infants with vs. without complicated birth
  • Phenols in serum, urine and body fluid in healthy and ill premature babies
  • Improvement of quality of life by introducing different hygiene schemes for children suffering from mucoviscidosis
  • Information level of doctors and midwives regarding nutrition of infants and toddlers
  • Case-series of children with craniosynostosis
  • Evaluation of plagiocephaly – a prospective study featuring a method comparison
  • Klinische Verläufe nach Hüftgelenksrekonstruktion bei Kindern mit spastischer Cerebralparese
  • Epilepsia in toddlers – risk factors, diagnostics and prognostic factors
  • Treatment of renal reflux and renal insufficiency after urinary tract infection in children
  • Improvement of overall fitness and quality of life as well as weight reduction in individual training vs. standard training
  • Coherence between colour visual field and cognitive abilities in children at primary school age
  • Prevalence of speech development disorders at different age levels – a cohort study
  • Die Anwendung des Akkusativs als Marker der kognitiven Entwicklung bei Schulkindern
  • Alcohol intoxication in adolescents: Risk factors, outcome and predictors for alcohol addiction
  • Risk factors for hepatocellular carcinomas in children
  • Prognostic relevance of different inflammatory markers in septic children suffering from leukaemia
  • Quality of life in juvenile idiopathic arthritis – comparison of different scores (PedACR, the DAS28 and the JADAS) and definition of a gold standard
  • Influence of the time of operation in acute appendicitis in toddlers – can an early operation improve the outcome?
  • Disease management in children suffering from oncological diseases

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Neurology

Interventional Neurology / Stroke / Subarachnoidal Haemorrhage

stroke
  • Laboratory markers to diagnose the extent of infarcted region in stroke patients
  • Interventional treatments of apoplectic insult: Comparison of different treatment strategies as well as independent risk factors for secondary symptomatic hemorrhages
  • Moment of ventilation after apoplectic insult as prognostic factor – a comparison of different treatment processes
  • Courses of symptomatic haemorrhages as secondary event after apoplectic insults
  • Significance of the transcranial Doppler to determine the size of infarcted region in ischemic insults and acute hemorrhages
  • Measurement of facial asymmetries in facial paralysis after apoplectic insult – which parameters influence the extent of the asymmetry?
  • Clinical course in patients with Facial Nerve Paralysis after surgical treatment by complete transposition of the temporalis muscle
  • ASS-Nonresponse in recurring apoplectic insults
  • Evaluation of the cognitive performance before and after carotid stenting by means of neuropsychological test procedures
  • Mirror movements and quality of life after apoplectic insults
  • Quality of life and change of social structures of patient and caregivers after juvenile insult
  • Aneurysms of cerebral vessels – morphology, localization and comparison of different treatment processes
  • Surgery of subarachnoidal hemorrhage – comparison of several treatment strategies – a multicenter study
  • Comparison of haemorrhage volumes (IVH) and intrahospital mortality after conservative vs. surgical treatment processes in intracerebral brain haemorrhages
  • Prognostic factors for a three-month survival rate after cerebral haemorrhage under the influence of oral anticoagulants
  • Invasive management of cerebral vasospasms after subarachnoidal hemorrhages
  • Comparison of surgical vs. conservative treatment after subarachnoid hemorrhages – a follow-up study
  • Influence of anticoagulation on the extent and course of intracerebral hemorrhages
  • Determinants of outcome after subarachnoidal hemorrhages considering different surgery strategies
  • Retrospective follow-up study of patients with glioblastoma, who were treated with a new surgery strategy
  • Long-term outcomes in patients with ACTH-secreting pituitary adenoma
  • Motoric and cognitive performance before and after surgery of different brain Tumors
  • Mortality of patients with cerebral tumours under the influence of combined treatment of surgical repair and Avastin – a pilot study
  • Results after surgery of Chiari malformation
  • Diagnostics of lumbal spinal stenosis by means of MRI considering influencing factors related to positioning
  • Comparison of outcome in surgery of lumbal spinal stenosis: Laminectomy vs. undercutting
  • Comparison of long-term results after laminectomy vs. laminotomy in lumbal spinal stenosis

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Conventional Neurology

neurology
  • Laser treatment in patients with multiple sclerosis – follow-up study with SF-12
  • Fatigue and cognitive abilities in patients suffering from multiple sclerosis
  • Chronic pain in patients with Parkinson´s disease – influence of pain medication and antidepressants
  • EEG monitoring in patients with vs. without deep brain stimulation. Which localization of the stimulation electrodes proves the best results?
  • Interpretation of sleep-deprivation EEGs in patients suffering from epilepsy
  • Interdependence between the BOLD effect (Blood Oxygenation Level Dependence) and muscle activity in athletes
  • Interpretation von Schlafentzugs-EEGs bei Patienten mit Epilepsie
  • Zusammenhang zwischen dem BOLD-Effekt (Blood-Oxygenation-Level-Dependence) und der Muskelaktivität bei Sportlern
  • Mental illness as trigger for the increase of carotid intima-media thickness
  • Diagnostics of the minimal hepatic encephalopathy in patients with alcohol-related liver cirrhosis
  • Clinical symptoms and laboratory developments in posterior reversible leukoencephalopathy
  • Anomalies of the paranasal sinuses as cause of therapy-refractory migraine
  • Therapy results in migraine with Botox® (botolinum toxin) injection – an international multicenter study with more than 7000 patients
  • Model development for the prediction of course and intensity of migraine – a multi-centre study including 15.000 patients
  • Independent predictors for a therapy-refractory migraine – is the course of a migraine predictable?
  • Closure of a persisting foramen ovale in therapy-refractory migraine
  • Deterioration of quality of life in epilepsy – implementation of SF-36 and validation of assessment systems
  • Epilepsy in children and adolescents – Imaging, clinical factors and clinical course
  • Diagnostic validity of CCT and MRI in epilepsy
  • Determination of cerebral compression in brain tumors – does the MRI represent an alternative to lumbar puncture?
  • Fundamental research: Amplitude and latency of stimulus responses of healthy study participants after multiple stimulation of the ulnar nerve
  • Improvement of motoric performance and quality of life by intensive physiotherapy treatment in patients with muscular dystrophy
  • Psychic strain and work stress in caregivers in the field of Neurology – implementation of the COPSOQ score

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Psychiatry / Psychology / Quality of Living

Psychiatry
  • Dissociative phenomena in patients suffering from different psychosomatic primary diseases
  • Significance of neopterin, phenylalanin, serotonin, CD14, TRP and the Hamilton score to evaluate the course in patients suffering from depression
  • Occupational gratification crises of managers – correlation between work ability index and the ADS scores
  • Applying the SF-36 on different employees´ groups in large companies with different levels of sense of coherence
  • Gender-specific differences regarding coping in illnesses of the endogenous spectrum
  • Influence of short-term psychotherapy on the personality of patients with neurotic disorders
  • Time management and procrastination in students – a survey
  • Influence of birth complications and prenatal stress factors on disorders of emotional and social development
  • Comparison of sexual development and one´s own sexual perception in hetero vs. homosexual tendency
  • Diagnosis of psychiatric diseases in recent decades: Epidemiologic influencing factors on changes in illness incidences
  • Influence of benzodiazepine on mortality in patient with endogenous psychoses – a long-term study
  • Comparison of schizoaffective disorders: risk factors, therapeutic procedures and long-term courses
  • Cerebrovascular reactivity in endogenous depression
  • Improvement of endogenous depression by administration of plant concentrates
  • Effectivity of therapy programmes for children with aggressive behaviour
  • Behavioural syndromes and cognitive disorders in children suffering from haemolytic and oncological diseases - evaluation of the Kindle questionnaire
  • Inflammation parameters in endogenous psychoses: course of disease under medicinal therapy
  • Comparison pro-inflammatory vs. anti-inflammatory interleukin in serum and liquor in bacterial, viral and demential cerebral diseases
  • Case series of 2 drugs in patients with somatoform disorders
  • Coincidence of internet, computer and television addiction – personality characteristics and influence on the quality of life
  • Comparison of effectivity of different smoking cessation programmes
  • Influence of internet behaviour on the compliance in patients suffering from endogenous psychoses
  • Medical treatment of the side effects of alcoholic stupor – a case series
  • Developments in EEG potentials, neuro-psychologic and psychometric tests regarding alcohol addiction
  • Influence of serotonin polymorphisms on the development of depression in patients with alcohol abuse
  • Influence of the pitch of voice on the acceptance of top executives
  • Comparison of satisfaction of hospital patients in different Asian countries
  • QLQ-C30, SWE, HADS-Scale and resilience scale in oncologic patients
  • Validity of the evaluation of anxiety and depression by means of the HADS Scale in different gynaecologic tumours
  • Evaluation of pain (BDI questionnaire) and FFbH-P (function questionnaire Hannover) in patients with chronic polyarthritis under optimized therapy
  • Quality of life in presbyacusia in patients with vs. without hearing aid
  • Delirium and quality of life after hip fractures in patients with dementia
  • Influencing factors on the quality of life (QLQ-C30 scales) in prostate carcinoma
  • Development of a new questionnaire for the assessment of the satisfaction of students: Validation and reliability analysis (Cronbach´s α)
  • Mental strain and work stress in nursing staff – implementation of the COSOQ score
  • Influence of endogenous and exogeneous stressors on cognitive performances
  • Influence of education on psycho-social stress of oncology nurses (implementation of EWL, AVEM and SF-36)

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Community Medicine

community medicine
  • Manipulation of expert opinion caused by answer bias in psychiatric patients
  • Religiöse und kulturelle Einflüsse bei der Sterbebegleitung von geriatrischen Patienten 
  • Todesangst und Erwartungen am Lebensende – ein Vergleich der Generationen 
  • Vergleich der Einnahme von Medikamenten und Alkohol bei Patienten verschiedener ethnischer Herkunft 
  • Kompetenzgewinnung durch tiefe Stimmlage von Führungskräften
  • Wissen über Ergonomie und Prävention von Überlastungen am Büroarbeitsplatz
  • Soziale und epidemiologische Aspekte beim Alkoholabusus von Jugendlichen
  • Einfluss des Alkoholmissbrauchs der Eltern auf die Trinkgewohnheiten der Kinder – eine internationale Studie mit 2500 Fällen

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Geriatrics

geriatrics
  • Drops in hospitals and their outcome – a long-term follow-up
  • Risk factors for delirium after hip placement in geriatric patients
  • Risk factors for malnutrition after elective surgeries in geriatric patients
  • Comparison of medication and therapy recommendations in geriatric patients at discharge from acute care hospital after 4 weeeks – which therapies are considered?
  • Predictive value of laboratory parameters in the rehabilitation of geriatric patients
  • Learning progress in geriatric and demential patients – influences of environmental factors, learning methods and nutrition
  • Positive and negative predictors of rehabilitation prognosis – significance of the ADL- and Tinetti score
  • Indication of abdominal sugeries in octogenarians – an analysis covering the last 25 years

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Sports Medicine

sports medicine
  • Controlled weight loss achieved by individuell sports programme in patients with BMI > 30
  • Influence of sports activities on motoric skills in demential disease
  • Increase of quality of life and performance thanks to individual workout programmes in patients with tumorous diseases
  • Comparison of bodily fitness with different types of sports – optimization of success due to differentiated training programmes
  • Improvement of performance in patients suffering from arterial hypertonia due to training programmes
  • Quality of life, fitness and change of lifestyle before and after Five Tibetan exercises
  • Influence of competitive sports on dental health and prevalence of dental injuries
  • Prophylactic administration of throat pastilles to avoid infections in competitive sportsmen/sportswome
  • Prevalence of atrial fibrillation in former handball athletes – anatomic and functional modifications of the left atrium and ventricle as risk factor for atrial fibrillation.
  • Effects of competitive sports on echocardiographic parameters – a long-term study
  • Influence of caffeine on the speed of top-athletes
  • Influence of sporting activities of general practitioners on the evaluation and treatment of sports injuries
  • Physical fitness and course of body weight in adipose patients – long-term course and comparison of different sports programmes
  • Comparison of increase of strength by different forms of physical training – what additional benefit do training machines have?
  • Effects of neuropsychological norm variants of the ankle joint on performance
  • Which diagnostic benefit does the echocardiography have in sports medical screening examinations of top athletes?
  • Influence of age on echocardiographic abnormalities in top athletes
  • Comparison of ECG abnormalities in recreational athletes vs. top athletes
  • Prevalence of arterial hypertonia in recreational athletes – a multi-centre long-term project

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Dermatology

dermatology
  • Reduction of subcutaneous fat by topical medication of lipolytic agents
  • Reduction of subcutaneous fats by topical application of lypolytic agents
  • Risk factors for lipodystrophy in HIV patients considering genetic factors
  • Comparison of histochemical staining in malign melanoma – which staining is best-suited? 
  • Diagnostic validity of microscopic grey scale analysis in different skin tumors
  • Determinants of survival in malignant melanoma – a 10-year analysis
  • Sensivitity and specificity of the dermatoscopy in melanocytic nevi and malign melanoma
  • Comparison of prognostic validity of several tumor markers in malign melanoma
  • Predictive value of the Su-Par in malign melanoma – a model development by combining prognostic parameters
  • Outcome in basal cell carcinoma – a multicenter study with 2000 patients
  • Incidence of malign melanoma between 1979 and 2003. Description of modification of localization, histological subtypes and patients´ characteristics
  • Sensitivity and specificity of antibodies in dermatomyositis and polymyositis
  • Evidence of auto-antibodies in patients with collagenase and non-rheumatic inflammatory diseases
  • Diagnostics and medical treatment of drug induced exanthemas
  • Success rates of hyposensibilisation in patients with anaphylactic reactions after wasp stings
  • Comparison of different treatment procedures of Osler´s disease
  • Prospective studies in patients with lipoedema and liposuction treatment
  • Lymph therapists´ standard of knowledge regarding diagnostics and therapy of lipoedema Comparison of treatments of lipoedema in different professional Groups
  • Comparison of lipoedema treatments in different occupational groups
  • 6 month-results after liposuction in female patients suffering from lipoedema
  • Long-term outcome after liposuction in patients with lipoedema
  • Definition of new measuring methods to determine body measurements of female patients suffering from with lipoedema
  • Quality of life after liposuction in female patients with lipoedema
  • Prevalence and clinical symptoms of the lipoedema in GP care
  • Venous and lymphological diseases of the lower extremities in women – an epidemiologic survey including 1000 women
  • Coriumdicke vor und nach KPE bei Patientinnen mit Lymphödem
  • Prevalence of varicosis in GP care – evaluation of different therapeutic regimes

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 Microbiology / Virology / Immunology

Microbiology
  • Evidence of ESBL by means of different methods as well as comparison of effectiveness of several antibiotics combinations
  • Case series: Implementation of bone cement containing antibiotics on staphylococci
  • Comparison of sensitivity and specifity of different laboratory methods in the reprocessing of blood cultures
  • Change of germ spectrum and development of resistances within the last 15 years – an analysis of 70.000 blood cultures
  • Prevalence of multi-resistant germs in the ambulance – a comparison of several rescue systems
  • Bacterial communities in different university clinics – comparing germ spectrums and resistances
  • An internationally sponsored project: New sanitary facilities in schools in developing countries – effects on hygiene and school attendance
  • Diagnostics and treatment of bacterial communities in deep wounds
  • Anti-bacterial effect of ozone gas in different concentrations – which experimental arrangements has the best antibacterial effect?
  • Elimination of chronic bacterial infestation by laser therapy
  • Courses of rickettsia diseases – diagnostic value of different laboratory parameters
  • Patient collective and symptoms in Lyme disease
  • Sensitivity and specificity of a new form of PCR diagnostics for the identification of pathogens in patients suffering from leishmaniasis
  • Prevalence of postinfectious irritable bowel syndrome after journeys to tropical and subtropical regions regarding different pathogens – an interdisciplinary long-term study
  • Viral load of cardiotropic viruses in competitive athletes compared to a healthy comparison group
  • Reasons for omitting vaccinations for infants and school children: a survey of 2000 cases
  • Courses of measles infections – influence of age, sex and vaccination behaviour
  • Epidemiologic parameters and courses of measles infections – comparison of different European countries
  • Application of immune supporting substances as supplementary balanced diet (SBD) – proof of first successful cases after introduction
  • Epidemiologic risk factors for healthy cMRSA carriers – is there a predisposition due to animal husbandry and professional exposition?
  • Reduction of mortality and complication rates in newborns by intensified smear tests and specific early treatment of bacterial infections
  • Correlation of virus infections with occurrence of haemorrhagic cystitis after allogeneic stem cell transplantatio
  • Effectivity of different antifungal prophylaxes after allogeneic haematopoietic stem cell transplantation
  • Comparison of microbiologic detection procedures in spondylodiscitis
  • 10-year follow-up study of HIV patients
  • Drug resistance in HIV diseases
  • Mutations in HIV patients under different drug regimens
  • Extent of lipodystrophy in HIV patients and consideration of genetic and epidemiologic factors
  • Predictors for mortality in HIV patients and improvement of outcome by early treatment initiation and inpatient treatments
  • Cardio-vascular risk factors and manifestations of CHD in HIV patients – a long term study
  • Influence of the HIV disease on intima thickness

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Laboratory medicine / Clinical Chemistry / Haemostaseology

Laboratory medicine Haemostaseology
  • Influence of the FV Leiden mutation on coagulation parameters and antibodies – a systematic analysis of 9.000 laboratory tests
  • Influence of the von Willebrand disease and haemophilia on pregnancy complications
  • Effects of polymorphisms of the von Willebrand factor on concentration and activity of the von Willebrand factor
  • Homocygous and heterocygous polymorphisms of the PAI-1 and their influence on the PAI-1 concentration in the serum
  • Influence of different polymorphisms of the FVII on the FVII concentration
  • Complications and long-term courses in different therapeutic strategies in patients suffering from haemophilia
  • Clinical relevance and coincidence of JAK2V617-, CALR- and MPLW515L/K mutations in essential thrombocythaemia and primary myelofibrosis
  • Diagnostics and therapy of patients with haemophilia A – a retrospective acquisition over a period of 20 years
  • Influence of polymorphisms and haematological anomalies on habitual abortions – a prospective study
  • Prognostic value of anomalies of the protein C and S as well as coagulation factors on the abortion risk – a multicentre study
  • PFA-time in patients suffering from ASS – Evidence of non-responders in recurring apoplectic insults
  • Validation of a new measuring method to measure heparine concentration after extracorporeal circulation with laser nephelometry
  • Fractal and euclidean descriptors of platelet shape
  • Automatic detection of changes in platelets shapes
  • Reliability of low molecular heparins regarding the prevention of deep vein thrombosis – a multicentre case series of 2000 patients
  • Selenium concentration in the serum after substitution in patients with inflammable or cancerous diseases
  • Influencing factors on the water quality and its meaning for general health
  • Therapeutical effects and side effects of Bentonit – a clinical evaluation
  • Therapeutical effects and side effects of Zeolite – a clinical evaluation
  • Course of 13-Hode after therapy with intravenous oxygenation
  • Laboratory analysis of different forms of vitamin B6 – validation of a new measuring method
  • Effect of an adjuvant sepsis therapy on inflammatory laboratory parameters and the mortality compared to a standard therapy
  • Predictive value of copeptin in heart attack diagnostics

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Forensic Medicine 

forensic medicine
  • Influence of cause of death and time of agony on post mortem urinary bladder filling volume
  • Size of burning area and type of burning in attack victims, accidents and attempted suicide
  • Cause of death and circumstances in 2000 suicide victims
  • Reliable characteristics for the identification of corpses in catastrophies with multiple fatalities
  • Trends in organ donation within the last two years – can any influence of media campaigns be detected?

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Radiology/ Nuclear Medicine / Nuclear Magnetic Resonance Imaging

radiology magnetic Resonance Imaging
  • Comparison of scintigraphic methods in diagnosis of toxic thyroid adenomas
  • Diagnostic value of NMRI in different histologic forms of breast cancer – relevance of hydrated tissue Proportion
  • Sensitivity and specifity of NMRI in the diagnosis of cervix carcinoma
  • Radiologic follow up of stabilising spine procedures in geriatric patients
  • Cardiac MRI as screening method for the initial diagnosis of CHD
  • Positron emission tomography for the evidence of improvement of the coronary flow reserve by statins in patients suffering from coronary diseases
  • Computer tomographic examination techniques in patients with different congenital heart defects
  • Comparison of different sequences of the MRI – what image generates the most exact precision and reproducibility when imaging different joints?
  • Cartilage assessment by means of native MRI and d-Gemric (delayed Gardolinium Enhanced Cartilage)
  • Reproducibility of different radiological imaging procedures of the upper arm under clinical routine circumstances
  • Volume determination by means of computer tomography after the implementation of chemoembolization and microwave ablation technique in different tumours
  • Determination of reference values of diameters and organ dimension in computer tomography under consideration of age and sex
  • Predictive values of punch biopsies of different localisations in case of suspected neoplastic neoformations
  • Validity of cartilage-sensitive MR sequences in the diagnosis of medial meniscal tears

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Quality Management

quality management
  • Evaluation of satisfaction in everyday working routine of different professional groups before and after introducing quality management
  • Service offer in primary health care hospitals before and after introducing the DRG system
  • Improvement of patient care by routinely assessment of SAPS II and APACHE in the intensive care ward
  • Improvement of the satisfaction of patients and GPs by standardised medical reports
  • Satisfaction of patients and GPs in a large hospital – which approaches regarding optimization can be identified?
  • Objectification of selection criteria of medical students – which factors identify a successful graduate?
  • Acceptance of quality management by leading qualified teachers – a survey throughout Germany
  • Evaluation of new concepts integrating community nurses in GP practices – effects on quality of diagnostics and therapy
  • Range of services in different statutory health insurances – analysis of preventive programmes
  • Analysis of sources of error in perfusion and pump systems in university clinics – can improvements after the optimisation of quality management be proven?
  • Preoperative predictors for the identification of complicated intubations before elective surgery – avoidance of complications in elective intubations
  • Influence of quality management in bariatric surgery on postoperative processes
  • Influence of composition and experience of the OP team on efficiency and OP results
  • GP care before and after changes in liquidation options – range of service and quality of treatment in times of rationalisation
  • Quality management and GCP-according implementation of clinical studies with medical products

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Dentistry

Conservative Dentistry and Parodontology

Conservative Dentistry and Parodontology
  • Sensitivity and specifity of caries diagnostics in different radiologic procedures
  • Consecutive dental findings of orthopantomograms in a large collective – incidence of caries in different age groups
  • In vitro study to evaluate hard tooth tissue in the approximal space
  • Association between age of amalgam fillings and probing depths, mobility grades and ryge criteria
  • Retrospective evaluation of the length of survival of teeth after direct capping with calcium hydroxide
  • Determination of mechanic strength values in modified tooth composites
  • Marginal density of the orthograde root filling after apicoectomy – comparison of different materials by means of electron-microscopic examination
  • Fracture rate of endodontic files with due regard to the „Wave One“
  • Long-term course after root filling – influencing factors on loss rate
  • Comparison of progress after root filling over a period of 20 years – long-term success of different treatment techniques and indications
  • Identification of independent determinants of failed root canal treatments
  • Comparison of long-term courses after different techniques of root canal treatment
  • Bleaching of devital teeth
  • In vitro study on the toxicity of bleaching treatments
  • Influence of brush abrasions (in vitro) on dentin and enamel
  • Correlation between dental hygiene and bacterial profile before and after treatment of patients and their relatives
  • Comparison of bacterial colonisation of healthy teeth, gold and ceramic caps in patients suffering from parodontitis
  • Decrease of quality of life due to parodontitis
  • Predictive values of risk factors for parodontitis – establishment of a new risk score
  • Influence of rheumatism on parodontitis – an interdisciplinary study
  • Diabetes-Screening in dental practice using the Find-Risk questionnaire – a practice based pilot study
  • Importance of aliphatic acid on parodontitis in patients with rheumatoid diseases
  • Standard of knowledge of dental assistants regarding caries and parodontitis prevention
  • Effects of chemotherapeutics on the vitality of bacteria on enamel and dentin
  • Coincidence of carotid calcifications in patients with progressed parodontitis
  • Influence of rheumatoid diseases on the prevalence of parodontitis
  • Association between immunosuppressive therapy in rheumatoid diseases and parodontal diseases
  • Patient characteristics in clinical treatment processes in dental medicine – a comparative analysis covering 2 decades
  • Validation of a new questionnaire regarding patient satisfaction after parodontal treatment
  • Diagnostics of parodontitis – of what significance is the MMP 8 rapid test?
  • Association between MMP-8 and parodontitis in patients suffering rheumatoid Arthritis
  • Adjuvant administration of ethereal oil in parodontitis treatment
  • Level of knowledge of practising dentists regarding diagnostic and therapeutic procedures in endodontics
  • Influence of tooth position and oral health on quality of life
  • Influence of different rinsing solutions on the bacterial colonialisation in endodontic treatments
  • Dental chart dependent on nutrition and oral hygiene in adolescents – a questionnaire study
  • Relation between social factors and dental health
  • Dental health after bone marrow transplantation
  • Influence of high-performance sport on dental health – prevalence of dental fractures in combat sport
  • Significance of oral irrigators in the daily interdental and gingival hygiene / parodontal Hygiene
  • Efficiency validation of Dental Water Jets in additive implementation of Full Mouth Disinfection (FMD) without antibiotherapy, verified by the polymerase chain reaction
  • Evidence of rantes in tissue and serum in different inflammatory dental processes
  • Evidence of mycoplasma with PCR in endodontic Treatment
  • Competence of dentists in the treatment of life-threatening emergencies in the practice
  • Patients in a dental polyclinic during the emergency consultation hours – epidemiologic factors, accident progress and prognostic factors for tooth conservation
  • Analysis of diseases with hypoplastic incisors

Materials Science / Prothetic Dentristry / Propaedeutics

Werkstoffkunde / Prothetik / Propädeutik
  • Comparison of different ceramic Systems
  • Quality and resilience of different ceramic veneers
  • Comparison of treatment possibilities of dental hard tissue loss in the posterior region
  • Comparison of retentive strength and surface loadability in test series with differing depths of canal inlay with vs. without retention
  • Comparison of fracture stability of different denture materials
  • Successes in selective laser intensity in dentistry
  • Analysis of cement gaps and marginal gaps in bridges using different materials
  • Influence of breaking loads after use of different materials and adhesion techniques
  • Influence of dental pin conditioning on adhesion of dental pins in the root canal – an in vitro study
  • Determinants of the temperature development of dentine in preparation – an in vitro study
  • Quality comparison of implant impression techniques by using different impression materials
  • Implant impression techniques in different new impression materials – a follow-up study
  • Comparison of several dental prostheses – aftercare, repairs and risk of loss
  • Bacterial contamination of sterilised dental instruments – comparison of different German state
  • How high is the proteine contamination of purified and sterilised operating materials?
  • Survival rate of inlays – comparison of different materials
  • Dimensional accuracy of impression material in open and closed implant impressions
  • Dimensional precision of different impression techniques using the Xive® implant system

Implantology / Oral and Maxillofacial Surgery /Medical Imaging

Klinische Studie Implantologie
  • Prognostic factors in squamous cell carcinoma of the head and oral cavity considering different operation methods
  • Influence of different modified extirpations on long-term course in squamous cell carcinoma of oral cavity and paranasal sinuses
  • Risk factors for mortality in floor of mouth cancer
  • Survival analysis of patients suffering from tongue carcinoma
  • Influence of epidemiologic factors and lifestyle on sensibility, taste perception and perception of pain of the tongue
  • Osteoradionecrosis of the mandible – a follow-up study covering 15 years
  • Implementing hypnosis procedures during tooth extractions: Acceptance by patients and influence on pain and fear experience
  • Therapy of injuries of the mandibular nerve caused by traumata with electro acupuncture
  • Information level of patients about dental implants
  • Bone loss in implants of the maxilla – a long-term study
  • Influence of bone training on the implant-bone-interface in different implant systems
  • Bone loss in mandible implants – which risk factors can be identified?
  • Long-term results of immediate implant treatment in geriatric patients
  • Immediate loading after implant treatments in the non-dentate jaw – analysis of the influence of localisation and patient-related influence factors
  • Influencing factors on aesthetics in implantology
  • Quality of life and satisfaction of patients with implant-supported dentures
  • Genetic factors for implant loss – analysis of polymorphisms
  • Occuring of peri-implantitis in different implant systems with vs. without phosphoric acid etching
  • Comparison of Bio-Oss® vs. other implantation material regarding the occuring of peri-implantitis
  • Histological results after maxillary sinus augmentation – comparison of different bone replacement materials
  • Complications after use of membranes in sinus lifts – a review
  • Proof of microbiologic contamination of implant cavities after use of different fillers
  • Avoidance of peri-implantitis by using oral water jets
  • Stability of implants in two methods of insertion: transgingival placement vs. gingival detachment
  • Bone loss after different implant systems – a clinical cohort study
  • Risk factors depending on operation technique and patient for implant failure in dental everyday practise – a long-term observatio
  • Long-term courses after osteosynthesis procedures with different materials
  • Covering of multiple recessions with a collagen matrix vs. enamel matrix protein in combination with the tunneling technique
  • Performance measurement after gingivo-periostoplasty in patients with clefts
  • Mandibular reconstruction with iliac crest graft – a long-term study
  • Quality comparison of 3 different X-ray systems as well as the comparison of reliability between first and second examination for the respective examiner
  • Examiner-dependent diagnosis of panoramic X-rays – analysis of kappa coefficients of dentists with different standards of education
  • Comparison of exactness and interobserver variability in the use of hanel occlusion foil vs. T-scan
  • Improvement of interobserver variability in cephalometric diagnoses thanks to intensified training
  • Examiner-dependent diagnoses of lateral cephalograms – analysis of kappa coefficients of dentists with different standards of education
  • Comparison of the accuracy of details of digital sensors, the conventional dental film and imaging plates in everyday clinical practise as well as an evaluation by different observers
  • Radiation exposure and interobserver variability in conventional bitewing radiograph vs. orthopantomograms
  • Implementation of Bio-Oss®in everyday dental practise – a monocentric experience
  • Breaking load of different types of implants
  • Stability values in the jaw bone of implants with different outer forms
  • Comparison of manual vs. digital measurements for the grading of tooth misplacements
  • Bone resorption in different bone replacement materials after sinus floor elevation

Orthodontics

orthodontics
  • Einflussfaktoren auf die Prävalenz von radiologisch gefundenen Zufallsbefunden in der Kieferorthopädie
  • Definitions of standard values in the measuring of the respiratory tract in the CAT scan
  • Measuring of the maxilla in different tooth displacements
  • Definition of standard values in the measuring of the maxilla in the CAT scan – an analysis with Osirix
  • Measuring of maxilla with CAT scan to determine suitable localizations for miniscrews
  • Measuring of dental root inclination in the CAT scan
  • Measuring of recessions and dehiscences in maxilla and mandible by means of CAT scan
  • Mobility of the jaw before and after dental treatment
  • Analysis of cephalometric and orthopaedic parameters before and after dental treatment in adolescents and adults
  • Results of long-term treatment in patients with cleft lip and jaw – analysis of dental, sagittal and vertical Parameters
  • Clinical evidence of asymmetries in cleft lip and palate in the CAT scan and MR imaging
  • Formation of the mucogingival junction in different areas of the maxilla and mandible – definition of suitable measuring points
  • Questionnaire evaluating resident dentists´ state of information regarding CMD – are symptoms of CMD recognized?
  • Questionnaire evaluating resident dentists´ state of information regarding CMD – how is CMD treated?
  • Resident dentists´ state of information regarding CMD – influence of epidemiologic data
  • Prevalence of CMD in the population, in university institutions and in dentists´ everyday practice – an epidemiologic study
  • Prevalence of CMD in patients suffering from advanced stage of psoriasis
  • Association between CMD and CCD – a clinical analysis
  • Diagnostics of CMD in patients with vs. without CCD – the significance of OPG 
  • Analysis of deformations of the cervical spine and cephalometric parameters in patients with symptomatic CMD
  • Cervical spine parameters in the lateral cephalogram in patients suffering from CCD compared to the normal population
  • Comparison of deformations of the cervical spine in patients with vs. without CCD – a follow-up study
  • Improvement of symptoms in patients with CMD – a prospective study comparing conservative and operative treatment strategies
  • Therapeutic success through laser acupuncture in patients with CMD
  • Association between psoriasis and CMD – diagnostics, therapy and prognostic determinants
  • Rantes´ in serum and tissue in CMD and the correlation with cycokines
  • Evaluation of lateral cephalogram according to the analysis of professor Pancherz before and after orthodontic treatments
  • Superimpositions in 3D X-ray images
  • Force vectors in orthodontics in the standard Edgewise and Straightwire technique
  • Patient expectations regarding the use of orthodontic mini pins – a comparison between two insertion and anaesthesia techniques  
  • Results of skeletally based molar distalization – a meta-analysis
  • The skeletal `Frog´ appliance for molar distalization
  • Effects of maxillary expansion – a systematic review
  • Molar distalization after treatment of class II malocclusions with the Herbst occlusal hinge
  • Application of different bracket ligature mechanisms – comparison of different forms of rotation various multi bracket apparatuses
  • Vergleich verschiedener Bracket-Bonding-Verfahren: Zeitbedarf und Langzeitergebnisse
  • Inclinations after therapy with the Lip Bumper
  • Use of the „tomas Uprighting Spring“ in the uprighting of molars – a case series
  • Distalization effects in skeletal anchorage
  • Influence of pins on side effects in the treatment with Herbst occlusal hinge
  • Influenceability of tinnitus with different medicinal therapies vs. use of dental splints   
  • Space closure with different pins – a case series
  • Prospective analytical study for the quantitative evaluation of the placing of miniscrews to detect clinically visible location markers
  • Influence of epidemiologic factors and oral hygiene on the loss of mini pins
  • Reliable coupling of orthodontic elements to mini implants with cross slots – an in-vitro examination
  • Effects of apparatuses for maxillary expansion on the extrathoracic plenum, epiglottis and hyoid. A retrospective kephalometric study.

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Osteopathy

osteopathy
  • Improvement of pulmonary capacity by specific osteopathic therapy in patients with different syndromes of the thoracic spine
  • Improvement of pulmonary function parameters by osteopathic treatment of the cervical spine
  • Mobility of upper pectoral girdle before and after osteopathic treatment
  • Influence of osteopathic therapy on the pulmonary function in children suffering from bronchial asthma
  • Reduction of airway resistance after osteopathic treatment in patients with chronic obstructive pulmonary diseases
  • Influence of osteopathic treatment on ophthalmologic parameters in patients with strabismus
  • Treatment of children suffering from obstipation with osteopathic procedures
  • Influence of osteopathic treatment on the ability to concentrate (d2 tests by Brickenkamp) in school children
  • Sensitivity and specifity of electromyographic parameters in test persons with shoulder muscle tensions as well as follow-up study after treatment
  • Influence of interaction between treating person and patient on the muscle tone
  • Influence of treatment of intrathoracic fascia on the sympathetic nervous system
  • Comparison of measurements of tension and tone of different muscle groups before and after treatment as well as determination of Kappa coefficient in diagnosis by different examiners
  • Influence of osteopathic treatment on pain, mobility and quality of life in patients with craniomandibular dysfunction
  • Improvement of pain and opening of mouth after osteopathic treatment in different grades of severity of craniomandibular dysfunction
  • Effectivity of osteopathic treatment as complementary therapy in chronic polyarthritis
  • Treatment of hip dysplasia of the child with osteopathic therapy
  • Improvement of chronic pain of the musculoskeletal system thanks to special forms of training and osteopathic treatment in athletes
  • Pain and quality of life after treatment of chronic back pain with myoreflex therapy
  • Influence of osteopathic treatment on hamstring muscles in riders
  • Osteopathic treatment of calcaneal spurs
  • Improvement of mobility and quality of life after osteopathic therapy in patients with lumbar spine complaints
  • Individual training structure and ostepathic therapy in amateur athletes with musculoskeletal complaints
  • Strength increase and improvement of complaints with aimed back and abdominal training in patients with tensions and chronic pain syndrome
  • Influence of osteopathic treatment techniques on abdominal tension
  • Limitations of mobility of the kidneys in arterial hypertonia before and after treatment
  • Osteopathic treatment of stress incontincence – a comparison of different treatment approaches
  • Validity of diagnostic findings of osteopaths – comparison of experienced examiners vs. beginners
  • Influence of osteopathic treatment on the descensus uteri
  • Improvement of quality of life with osteopathic treatment during pregnancy
  • Association of organ fixation as well as mobility decrease of lumbar spine, thoracic spine and hip joint in renal arterial hypertony
  • Empathy of osteopaths and its importance in the therapist-patient-relation
  • Osteopathic treatment of daytime sleepiness and sleeping disorders in patients with shift work
  • Determination of the Freiburger Persönlichkeitsinventar (Freiburger personality inventory) of osteopaths as well as comparison of 12 stanines with a normal collective
  • The relation between osteopath and patient – validation of a new questionnaire

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Veterinary Medicine

veterinary medicine
  • Increase of milk yield as well as of milk components with different therapy procedures
  • Influencing factors on the milk yield of calves and cows
  • Quality management in dairy cattle farming: Improvement of milk components, outflow and fertility
  • Reproductive behaviour of insects depending on environmental factors
  • Implementation of acupuncture in different animal species
  • Endotracheal anaesthesia in dogs – expiratory O2 and CO2 content with different anaesthetic procedures and CO2 absorbers
  • Fluorescence enhancement in tumor tissue – comparison of different cell cultures and validation of a new in vitro examination method
  • Bacterial, viral and parasitic attack of different mammal species under different housing conditions – a long-term evaluation over a period of 30 years
  • New treatment procedures in horses with acute or chronic arthritides of the coffin joint – comparison of different intraarticularly applied types of medication
  • Concentration and activity of myeloperoxidase in trotting horses as marker of oxidative stress in different training loads
  • Effectivity of eFSH on the number of produced follicles, number of ovulations and number of won embryos in mares
  • Effects of endometriosis on foaling and birth complications in mares
  • Comparison of the quality of the horse´s ejaculated semen at different points in time after different processing procedures – which method achieves the best results?
  • Diagnostic procedures in horses suffering colics
  • Seasonal endocrinological changes in donkeys and mules – definition of reference areas
  • Changes of glucose metabolism and insulin resistance in lactating cows
  • Veränderung des Glucosestoffwechsel und Insulinresistenz bei laktierenden Kühen
  • Risk factors for stillbirths in cows – observation of 2.500 cows and heifers
  • Influence of calcium level on peripartum complications in cows
  • Culling rates of calves and cows in large farms
  • Electrolyte balance of cows paripartum with vs. without calcium substitution as well as prevalence of hypocalcemia
  • Resistencies of E. colie in cattle under the therapy with different antibiotics
  • Genotyping of different E. coli strains in infections of small animals
  • Importance of calcium as promoting factors of birth dystociae in cows and heifers
  • Bovine neonatal pancytopenia
  • Therapeutic effects of iron substitution in the lacterion period on hematological parameters of cows and their newborn calves
  • Fertility and mortality of calves and cows in different farms
  • Diagnosis and evaluation of scabies in wild boars

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